NeutraKine® EPO Monoclonal antibody
NeutraKine® EPO Monoclonal Antibody for ELISA, Neutralization
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
ELISA, Neutralization
Conjugate
Unconjugated
CloneNo.
1D2H2
Cat no : 69019-1-Ig
Synonyms
Validation Data Gallery
| Neutralization |
Product Information
69019-1-Ig targets NeutraKine® EPO in ELISA, Neutralization applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | human Humankine EPO protein HZ-1168 |
| Full Name | erythropoietin |
| Gene Symbol | EPO/Erythropoietin |
| Gene ID (NCBI) | 2056 |
| RRID | AB_2918839 |
| Conjugate | Unconjugated |
| Form | Lyophilized Powder |
| Purification Method | Protein G purification |
| Storage Buffer | Sterile PBS. |
| Endotoxin | <0.1 EU/μg |
| Reconstitution | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Background Information
Erythropoietin (Epo) is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. EpoR, is a glycoprotein expressed on megakaryocytes, erythroid progenitors and endothelial cells. Epo also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
This antibody can be used to neutralize the bioactivity of EPO.
Reviews
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Katarina (Verified Customer) (12-10-2024) | Used for neutralization of human EPO in cell culture experiments. Works well, just needed a higher amounts of antibody for neutralization.
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