Product Information
12833-1-PBS targets Neuropeptide Y in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Neuropeptide Y fusion protein Ag3568 Predict reactive species |
Full Name | neuropeptide Y |
Calculated Molecular Weight | 97 aa, 11 kDa |
GenBank Accession Number | BC029497 |
Gene Symbol | Neuropeptide Y |
Gene ID (NCBI) | 4852 |
RRID | AB_10791890 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P01303 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.