Neuropeptide Y Polyclonal antibody, PBS Only

Neuropeptide Y Polyclonal Antibody for IHC, IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12833-1-PBS

Synonyms

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Validation Data Gallery

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  IHC staining of human brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 12833-1-AP (Neuropeptide Y antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 12833-1-AP (Neuropeptide Y antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas cancer using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas cancer using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas cancer using 12833-1-AP (same clone as 12833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12833-1-AP (Neuropeptide Y antibody) at dilution of 1:50 (under 25x lens). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using Neuropeptide Y antibody (12833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 12833-1-AP (same clone as 12833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using Neuropeptide Y antibody (12833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse eye using 12833-1-AP (same clone as 12833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using Neuropeptide Y antibody (12833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse eye using 12833-1-AP (same clone as 12833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using Neuropeptide Y antibody (12833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 12833-1-PBS in a different storage buffer formulation.

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Product Information

12833-1-PBS targets Neuropeptide Y in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Neuropeptide Y fusion protein Ag3568
• Full Name: neuropeptide Y
• Calculated Molecular Weight: 97 aa, 11 kDa
• GenBank Accession Number: BC029497
• Gene Symbol: Neuropeptide Y
• Gene ID (NCBI): 4852
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.