Neuromedin B Monoclonal antibody, PBS Only

Neuromedin B Monoclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G3B6

Cat no : 66781-1-PBS

Synonyms

neuromedin B, NMB

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Validation Data Gallery

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  IHC staining of human gliomas using 66781-1-Ig (same clone as 66781-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 66781-1-Ig (NMB antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66781-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 66781-1-Ig (same clone as 66781-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 66781-1-Ig (NMB antibody) at dilution of 1:500 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66781-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 66781-1-Ig (same clone as 66781-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66781-1-Ig (NMB antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66781-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 66781-1-Ig (same clone as 66781-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66781-1-Ig (NMB antibody) at dilution of 1:500 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66781-1-PBS in a different storage buffer formulation.

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Product Information

66781-1-PBS targets Neuromedin B in IHC, Indirect ELISA applications and shows reactivity with Human, mouse samples.

• Tested Reactivity: Human, mouse
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: Neuromedin B fusion protein Ag0842
• Full Name: neuromedin B
• Calculated Molecular Weight: 16 kDa
• GenBank Accession Number: BC007407
• Gene Symbol: NMB
• Gene ID (NCBI): 4828
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in pituitary gland, hypothalamus, pancreas and stomach. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo. (PMID: 15528253, PMID: 2458345).