Nesprin 3 Monoclonal antibody, PBS Only

Nesprin 3 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 68420-1-PBS
Clone No.1D1G12

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, IF-P, Indirect ELISA

C14orf49, FLJ25605, Nesprin 3

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

68420-1-PBS targets Nesprin 3 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Nesprin 3 fusion protein Ag26012 Predict reactive species
Full Name chromosome 14 open reading frame 49
Observed Molecular Weight110 kDa
GenBank Accession NumberBC146604
Gene Symbol Nesprin 3
Gene ID (NCBI) 161176
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ6ZMZ3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Nesprin 3 also known as C14orf49, SYNE3, belongs to the Nesprin family. Nesprin-3 is a type II transmembrane protein of the outer nuclear membrane and contains a C-terminal KASH domain and a series of spectrin repeats(PMID: 16330710). Nesprin-3, a protein that links intermediate filaments to the nucleus, regulates endothelial cell morphology, perinuclear cytoskeletal organization, and flow-induced cell polarization and migration. Nesprin-3 is robustly expressed in human aortic endothelial cells and localizes to the nuclear envelope(PMID: 21937718).

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