NRCAM Recombinant antibody, PBS Only

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  WB analysis of SH-SY5Y using 84690-1-RR (same clone as 84690-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 84690-1-RR (NRCAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84690-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 84690-1-RR (same clone as 84690-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84690-1-RR (NRCAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84690-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84690-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84690-1-RR against Human NRCAM were performed. The affinity constant is below 1 pM.

NRCAM Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84690-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Ng CAM related, Neuronal surface protein Bravo, neuronal cell adhesion molecule, KIAA0343, hBravo

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Product Information

84690-1-PBS targets NRCAM in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: NRCAM fusion protein Ag16237
• Full Name: neuronal cell adhesion molecule
• Calculated Molecular Weight: 1304 aa, 144 kDa
• Observed Molecular Weight: 144 kDa
• GenBank Accession Number: BC098401
• Gene Symbol: NRCAM
• Gene ID (NCBI): 4897
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q92823
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Neuronal cell adhesion molecule (NRCAM) is a member of the L1 subfamily of cell adhesion molecules (CAMs) that belong to the immunoglobulin superfamily (PMID: 11329126). NRCAM is a transmembrane protein composed of six Ig-like domains and five fibronectin type-III repeats in the extracellular region, with a highly conserved cytoplasmic tail. It is mainly expressed in the nervous system and is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM is also expressed outside the nervous system. Altered expression of NRCAM has been associated with tumor progression in diverse organs (PMID: 22182708).