NR2E3 Monoclonal antibody, PBS Only

• 

  WB analysis of pig retina using 66494-1-Ig (same clone as 66494-1-PBS)

  pig retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66494-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse retina using 66494-1-Ig (same clone as 66494-1-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66494-1-PBS in a different storage buffer formulation.

NR2E3 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 66494-1-PBS

Clone No.1G1D9

Host / Isotype

Mouse / IgG1

Reactivity

Pig, Mouse

Applications

WB, Indirect ELISA

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37

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Product Information

66494-1-PBS targets NR2E3 in WB, Indirect ELISA applications and shows reactivity with Pig, Mouse samples.

• Tested Reactivity: Pig, Mouse
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: NR2E3 fusion protein Ag5831
• Full Name: nuclear receptor subfamily 2, group E, member 3
• Calculated Molecular Weight: 45 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: BC041421
• Gene Symbol: NR2E3
• Gene ID (NCBI): 10002
• RRID: AB_2881859
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q9Y5X4
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]