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NR2E3 Monoclonal antibody, PBS Only

NR2E3 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Pig, Mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G1D9

Cat no : 66494-1-PBS

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37

Validation Data Gallery

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  • Western Blot (WB) analysis of pig retina tissue using NR2E3 Monoclonal antibody (66494-1-Ig)

    WB analysis of pig retina using 66494-1-Ig (same clone as 66494-1-PBS)

    pig retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66494-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse retina tissue using NR2E3 Monoclonal antibody (66494-1-Ig)

    WB analysis of mouse retina using 66494-1-Ig (same clone as 66494-1-PBS)

    mouse retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66494-1-PBS in a different storage buffer formulation.

Product Information

66494-1-PBS targets NR2E3 in WB, Indirect ELISA applications and shows reactivity with Pig, Mouse samples.

Tested Reactivity Pig, Mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NR2E3 fusion protein Ag5831
Full Name nuclear receptor subfamily 2, group E, member 3
Calculated Molecular Weight 45 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC041421
Gene Symbol NR2E3
Gene ID (NCBI) 10002
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]