NPRL2 Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

NPRL2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10157-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of HeLa using 10157-1-AP (same clone as 10157-1-PBS)

  WB result of TUSC4 antibody (10157-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-TUSC4 transfected HeLa cells. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse pancreas using 10157-1-AP (same clone as 10157-1-PBS)

  mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 10157-1-AP (TUSC4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse pancreas using 10157-1-AP (same clone as 10157-1-PBS)

  IP result of anti-NPRL2 (IP:10157-1-AP, 3ug; Detection:10157-1-AP 1:500) with mouse pancreas tissue lysate 4000ug. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 10157-1-AP (same clone as 10157-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 10157-1-AP (NPR2L,TUSC4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 10157-1-PBS in a different storage buffer formulation.

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Product Information

10157-1-PBS targets NPRL2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: NPRL2 fusion protein Ag0210
• Full Name: tumor suppressor candidate 4
• Calculated Molecular Weight: 44 kDa
• Observed Molecular Weight: 44-50 kDa
• GenBank Accession Number: BC002791
• Gene Symbol: TUSC4
• Gene ID (NCBI): 10641
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

NPRL2 (NPR2 Like, GATOR1 Complex Subunit) is a Protein Coding gene associated with Epilepsy, Familial Focal. As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. Homologous to yeast nitrogen permease (candidate tumor suppressor) (NM_006545, BC021984) gene encodes a protein of molecular mass of 50 kDa. Data by using overlapping and nested homozygous deletions methods indicate that this protein might be a tumor suppressor involved in the development of lung cancers.