NLRC3 Polyclonal antibody, PBS Only

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  WB analysis using 30455-1-AP (same clone as 30455-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30455-1-AP (NLRC3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30455-1-PBS in a different storage buffer formulation.

NLRC3 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 30455-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

30455-1-PBS targets NLRC3 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: NLRC3 fusion protein Ag32323
• Full Name: NLR family, CARD domain containing 3
• Calculated Molecular Weight: 115 kDa
• Observed Molecular Weight: 100-110 kDa
• GenBank Accession Number: NM_178844
• Gene Symbol: NLRC3
• Gene ID (NCBI): 197358
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q7RTR2
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells.