NLRC3 Polyclonal antibody, PBS Only

NLRC3 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 30455-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

30455-1-PBS targets NLRC3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NLRC3 fusion protein Ag32323 Predict reactive species
Full Name NLR family, CARD domain containing 3
Calculated Molecular Weight 115 kDa
Observed Molecular Weight100-110 kDa
GenBank Accession NumberNM_178844
Gene Symbol NLRC3
Gene ID (NCBI) 197358
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7RTR2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells.

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