MultiProTM 5CFLX Anti-Human TPM4 (2E12D12)

TPM4 Monoclonal Antibody for Single Cell (Intra)

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

CloneNo.

2E12D12

Cat no : G67244-1-5C

Synonyms

TM30p1, TPM4, tropomyosin 4, Tropomyosin alpha 4 chain

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Validation Data Gallery

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  Single Cell Sequencing experiment G67244-1-5C on Resting PBMC

  G67244-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G67244-1-5C on PBMC treated with 4hr LPS + TI

  G67244-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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Tested Applications

• Positive Single Cell (Intra) detected in: 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

Recommended dilution

• SINGLE CELL (INTRA): <0.5ug/test

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

G67244-1-5C targets TPM4 in Single Cell (Intra) applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Oligo Conjugate
• Type: Monoclonal
• Immunogen: TPM4 fusion protein Ag6947
• Full Name: MultiPro^TM 5CFLX Anti-Human TPM4 (2E12D12)
• Calculated Molecular Weight: 248 aa, 29 kDa
• GenBank Accession Number: BC037576
• Gene Symbol: TPM4
• Gene ID (NCBI): 7171
• Conjugate: 5CFLX
• Form: Liquid
• Storage Buffer: PBS with 1mM EDTA and 0.09% sodium azide
• Storage Conditions: 2-8°C

Background Information

TPM4 is a member of tropomyosins (TPMs), a multi-gene family of actin-binding proteins present in all eukaryotic cells. In muscle, TPMs are responsible for mediating contraction via regulation of the actin-myosin interaction. As to non-muscle cells, its proposed role is to stabilize the actin filaments by modulating the interaction with proteins that are responsible for the regulation of actin dynamics. The form of TPM4 in muscle has a higher molecular weight than the form found in non-muscle cells.