Product Information
67243-1-PBS targets MYH10 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | MYH10 fusion protein Ag17069 Predict reactive species |
Full Name | myosin, heavy chain 10, non-muscle |
Calculated Molecular Weight | 1985 aa, 230 kDa |
Observed Molecular Weight | 200-230 kDa |
GenBank Accession Number | BC150634 |
Gene Symbol | MYH10 |
Gene ID (NCBI) | 4628 |
RRID | AB_2882522 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P35580 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MYH10 (non-muscle II-b, NM IIB) is a member of non-muscle myosin II which plays fundamental roles in the maintenance of cell morphology, cell adhesion, and migration, as well as cell division. MYH10 is mainly present in nerve cells, megakaryocytes, and other non-muscle cells. It has been reported to mediate centrosome reorientation during cell migration and contribute to ciliogenesis. Overexpression of MYH10 has been observed in breast cancer.