MXD1 Polyclonal antibody

• Featured Product
• KD/KO Validated

MXD1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

6

Cat no : 17888-1-AP

Synonyms

MAD, MAD1, MAX dimerization protein 1, Max dimerizer 1, MXD1, Protein MAD

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Validation Data Gallery

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  WB analysis of mouse skeletal muscle using 17888-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17888-1-AP (MXD1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse skeletal muscle using 17888-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17888-1-AP (MXD1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse skeletal muscle tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 2 publications below
• WB: See 6 publications below

Product Information

17888-1-AP targets MXD1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MXD1 fusion protein Ag12037
• Full Name: MAX dimerization protein 1
• Calculated Molecular Weight: 221 aa, 25 kDa
• Observed Molecular Weight: 25 kDa
• GenBank Accession Number: BC098396
• Gene Symbol: MXD1
• Gene ID (NCBI): 4084
• RRID: AB_2147741
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
human	WB	Sci Adv; A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.; Authors - Austin G Holmes
human	WB	Mol Carcinog; PMID: 28543796; Authors - Datong Zheng ; KD Validated
human	WB	Leuk Res; PMID: 30419548; Authors - Chen Huan
human	WB	J Surg Res; The microRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes.; Authors - Xiliang Zhang
human	WB	Oncol Lett; miR-19a/b modulates lung cancer cells metastasis through suppression of MXD1 expression.; Authors - Wenxia Hu
human	WB	Cell Death Dis; HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway; Authors - Fei Xiong ; KD Validated