MTCL1 Polyclonal antibody, PBS Only

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  WB analysis using 25780-1-AP (same clone as 25780-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25780-1-AP (MTCL1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25780-1-PBS in a different storage buffer formulation.

MTCL1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 25780-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, canine

Applications

WB, Indirect ELISA

Synonyms

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Product Information

25780-1-PBS targets MTCL1 in WB, Indirect ELISA applications and shows reactivity with human, canine samples.

• Tested Reactivity: human, canine
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MTCL1 fusion protein Ag22718
• Full Name: KIAA0802
• Calculated Molecular Weight: 1905 aa, 209 kDa
• Observed Molecular Weight: 250 kDa
• GenBank Accession Number: BC040542
• Gene Symbol: MTCL1
• Gene ID (NCBI): 23255
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9Y4B5
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Microtubule cross‐linking factor 1 (MTCL1) is a MT‐regulating protein that plays essential roles in accumulating the non-centrosomal MTs into the apicobasal MT bundles. MTCL1, identified as a binding protein of the cell polarity‐regulating kinase, PAR‐1b/MARK2, is recruited to the Golgi membranes through interactions with CLASPs and AKAP450/CG-NAP, and promotes microtubule growth from the Golgi membrane. Western blot analysis detected MTCL1 at an apparent molecular mass of 250 kDa as indicated in the literature (PMID: 23902687, 28283581).