MPZL1 Polyclonal antibody

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  WB analysis using 29784-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 29784-1-AP (MPZL1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

MPZL1 Polyclonal Antibody for WB, ELISA

Cat No. 29784-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

PZR1b, PZR, Protein zero-related, Protein zero related, Myelin protein zero-like protein 1

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Tested Applications

• Positive WB detected in: A549 cells, HEK-293 cells, human placenta tissue, mouse kidney tissue, mouse liver tissue, rat kidney tissue, rat liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

29784-1-AP targets MPZL1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MPZL1 fusion protein Ag31532
• Full Name: myelin protein zero-like 1
• Calculated Molecular Weight: 29 kDa
• Observed Molecular Weight: 32 kDa
• GenBank Accession Number: BC007881
• Gene Symbol: MPZL1
• Gene ID (NCBI): 9019
• RRID: AB_3669695
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O95297
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Myelin protein zero-like 1 (MPZL1, also known as PZR) is a transmembrane glycoprotein that promotes the migration of hepatocellular carcinoma cells and is involved in extracellular matrix-induced signal transduction (PMID: 16702974; 8912526). Phosphorylated MPZL1 was linked to the regulation of cell adhesion and migration (PMID: 24296779; 18378677; 12410637). The expression levels of MPZL1 were also associated with malignant features of ovarian cancer (PMID: 31233194).