MPP3 Polyclonal antibody

• Featured Product
• KD/KO Validated

MPP3 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 14650-1-AP

Synonyms

Discs large homolog 3, DLG3, MAGUK p55 subfamily member 3, MPP3, Protein MPP3

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Validation Data Gallery

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  IHC staining of human lung cancer using 14650-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer using 14650-1-AP (MPP3 antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human lung cancer using 14650-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer using 14650-1-AP (MPP3 antibody) at dilution of 1:50 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human lung cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• IHC: See 2 publications below

Product Information

14650-1-AP targets MPP3 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MPP3 fusion protein Ag6246
• Full Name: membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
• Calculated Molecular Weight: 66 kDa
• GenBank Accession Number: BC056865
• Gene Symbol: MPP3
• Gene ID (NCBI): 4356
• RRID: AB_10949194
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

MPP3, also named as DLG3, belongs to the MAGUK family which interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP3 plays an important role in signal transduction.

Publications

Species	Application	Title
mouse	IHC	J Neurosci; PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.; Authors - Park Bokyung B
mouse	IHC	J Neurosci; MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.; Authors - Dudok Jacobus J JJ ; KO Validated