MORC2 Monoclonal antibody, PBS Only

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  WB analysis using 68530-1-Ig (same clone as 68530-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68530-1-Ig (MORC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68530-1-PBS in a different storage buffer formulation.

MORC2 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 68530-1-PBS

Clone No.1G12E7

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Synonyms

KIAA0852, MORC2, ZCW3, ZCWCC1

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Product Information

68530-1-PBS targets MORC2 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: MORC2 fusion protein Ag19605
• Full Name: MORC family CW-type zinc finger 2
• Calculated Molecular Weight: 970 aa, 111 kDa
• Observed Molecular Weight: 118 kDa
• GenBank Accession Number: BC136782
• Gene Symbol: MORC2
• Gene ID (NCBI): 22880
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q9Y6X9
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. It can be recruited by HUSH to target site in heterochromatin. MORC2 also recruits histone deacetylases, such as HDAC4, to promoter regions, causing local histone H3 deacetylation and transcriptional repression of genes.