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Product Information
30615-1-PBS targets MMP11 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | MMP11 fusion protein Ag31191 Predict reactive species |
Full Name | matrix metallopeptidase 11 (stromelysin 3) |
Calculated Molecular Weight | 55 kDa |
Observed Molecular Weight | 50-55 kDa |
GenBank Accession Number | NM_005940 |
Gene Symbol | MMP11 |
Gene ID (NCBI) | 4320 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P24347 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Matrix metalloproteinase 11 (MMP11), also named stromelysin-3, is a member of the stromelysin subgroup belonging to MMPs superfamily. The role of MMP11 in cancer progression has been shown by several preclinical observations: its expression promotes tumor take in mice, homing of malignant epithelial cells, cancer progression by remodeling extracellular matrix, and antiapoptotic and antinecrotic effect on tumor cells (PMID: 19509157, 26892540). MMP11 has a calculated molecular mass of 55 kDa.