MCP-1/CCL2 Polyclonal antibody, PBS Only

MCP-1/CCL2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29547-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of THP-1 using 29547-1-AP (same clone as 29547-1-PBS)

  Non-treated, and PMA, LPS and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 29547-1-AP (MCP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29547-1-PBS in a different storage buffer formulation.

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Product Information

29547-1-PBS targets MCP-1/CCL2 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: fusion protein
• Full Name: chemokine (C-C motif) ligand 2
• Calculated Molecular Weight: 99 aa, 11 kDa
• Observed Molecular Weight: 11 kDa
• GenBank Accession Number: BC009716
• Gene Symbol: MCP-1/CCL2
• Gene ID (NCBI): 6347
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

MCP-1, ( also named as CCL2) is a member of the chemokine family. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of MCP-1 is associated with severe acute respiratory syndrome coronavirus 2 infection.