Product Information
82852-3-PBS targets MAZ in IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | MAZ fusion protein Ag15200 Predict reactive species |
Full Name | MYC-associated zinc finger protein (purine-binding transcription factor) |
Calculated Molecular Weight | 477 aa, 49 kDa |
Observed Molecular Weight | 49-51 kDa |
GenBank Accession Number | BC041629 |
Gene Symbol | MAZ |
Gene ID (NCBI) | 4150 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P56270 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Myc-associated zinc-finger protein (MAZ) is a transcription factor with dual roles in transcription initiation and termination. MAZ can activate the expression of a variety of genes such as the c-Myc, insulin, VEGF, and RAS gene family and the serotonin 1A receptor. MAZ plays a critical role in the progression of various cancers including breast, prostate, liver, and so on. Deregulation of MAZ expression is associated with the progression of pancreatic ductal adenocarcinoma (PDAC)(PMID: 29414775).