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MAP3K7IP2 Recombinant antibody, PBS Only (Detector)

MAP3K7IP2 Uni-rAbTM Recombinant Antibody for Cytometric bead array, Indirect ELISA, WB

Host / Isotype

Rabbit / IgG

Reactivity

mouse, human

Applications

Cytometric bead array, Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

230118G2

Cat no : 82948-1-PBS

Synonyms

TAB2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TAB2 Recombinant antibody (82948-1-RR)

    WB analysis using 82948-1-RR (same clone as 82948-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82948-1-RR (MAP3K7IP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00082-3

    Cytometric bead array standard curve of MP00082-3

    Cytometric bead array standard curve ofMP00082-3, TAB2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82948-3-PBS. Detection antibody: 82948-1-PBS. Standard: Ag5742. Range: 0.625-20 ng/mL.

  • Affinity and Kinetic Characterization of 82948-1-RR

    Affinity and Kinetic Characterization of 82948-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82948-1-RR against Human TAB2 were performed. The affinity constant is 0.107 nM.

Product Information

82948-1-PBS targets MAP3K7IP2 as part of a matched antibody pair:

MP00082-3: 82948-3-PBS capture and 82948-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity mouse, human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen MAP3K7IP2 fusion protein Ag5742
Full Name mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Calculated Molecular Weight 76 kDa
Observed Molecular Weight77 kDa
GenBank Accession NumberBC035910
Gene Symbol MAP3K7IP2
Gene ID (NCBI) 23118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer 100% PBS pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].