MAD2L1BP Monoclonal antibody, PBS Only

MAD2L1BP Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2H3H1

Cat no : 68336-1-PBS

Synonyms

Caught by MAD2 protein, CMT2, KIAA0110, MAD2L1 binding protein, MAD2L1BP, RP1 261G23.6

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Validation Data Gallery

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  WB analysis using 68336-1-Ig (same clone as 68336-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68336-1-Ig (MAD2L1BP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68336-1-PBS in a different storage buffer formulation.

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Product Information

68336-1-PBS targets MAD2L1BP in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: MAD2L1BP fusion protein Ag7653
• Full Name: MAD2L1 binding protein
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 34 kDa
• GenBank Accession Number: BC002904
• Gene Symbol: MAD2L1BP
• Gene ID (NCBI): 9587
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

MAD2L1BP, also named as CMT2 and KIAA0110, belongs to the MAD2L1BP family. It may function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. MAD2L1BP interacts with the spindle checkpoint and coordinates cell cycle events in late mitosis. MAD2L1BP may play an active role to remove MAD2 from p55CDC and tether MAD2 for silencing the checkpoint.