Lumican Recombinant antibody, PBS Only

• 

  WB analysis using 85343-1-RR (same clone as 85343-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85343-1-RR (LUM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85343-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Recombinant protein using 85343-1-RR (same clone as 85343-1-PBS)

  Recombinant protein were subjected to SDS PAGE followed by western blot with 85343-1-RR (LUM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85343-1-PBS in a different storage buffer formulation.

Lumican Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85343-1-PBS

Clone No.242615H3

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

LUM, SLRR2D, LDC, KSPG lumican, 242615H3

---

Product Information

85343-1-PBS targets Lumican in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: lumican
• Calculated Molecular Weight: 38 kDa
• Observed Molecular Weight: 50-90 kDa
• GenBank Accession Number: NM_002345.3
• Gene Symbol: Lumican
• Gene ID (NCBI): 4060
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P51884
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Studies show that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. (PMID: 18949819; 22252641; 9761754; 22365843)