LSAMP Polyclonal antibody, PBS Only

• 

  WB analysis of human brain using 13600-1-AP (same clone as 13600-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13600-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 13600-1-AP (same clone as 13600-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13600-1-PBS in a different storage buffer formulation.

LSAMP Polyclonal Antibody for WB, Indirect ELISA

Cat No. 13600-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

13600-1-PBS targets LSAMP in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: LSAMP fusion protein Ag4542
• Full Name: limbic system-associated membrane protein
• Calculated Molecular Weight: 338 aa, 37 kDa
• Observed Molecular Weight: 64-68 kDa
• GenBank Accession Number: BC033803
• Gene Symbol: LSAMP
• Gene ID (NCBI): 4045
• RRID: AB_10597712
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q13449
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

LSAMP, also known as LAMP, is a 64-68 kDa heavily glycosylated neural cell adhesion molecule expressed on the neuronal dendrites and somata (PMID: 1688937; 8666243). LSAMP is a member of the IgLON family. The amino acid sequence of LSAMP is highly conserved among species. Human LSAMP shares 99% amino acid sequence identity with rodent LSAMP. The impact of LSAMP protein on neurite outgrowth and neuronal connectivity has been established in a wide spectrum of psychiatric disorders in humans (PMID: 26136648). In mice, lack of LSAMP protein seemingly leads to a deterioration in the ability to adapt to novel stressful environments and stimuli (PMID: 22155487).