Product Information
55497-1-AP targets LRRK2 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | leucine-rich repeat kinase 2 |
| Calculated Molecular Weight | 286 kDa |
| GenBank Accession Number | NM_198578 |
| Gene Symbol | LRRK2 |
| Gene ID (NCBI) | 120892 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5S007 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
LRRK2, also termed Dardarin and PARK8, belongs to the protein kinase superfamily and TKL Ser/Thr protein kinase family. It is a protein kinase whose role is not yet known. LRRK2 may play a role in the phosphorylation of proteins central to Parkinson disease. It may also have GTPase activity (PMID:16352719). Defects in LRRK2 are the causes of Parkinson disease type 8 (PARK8). This antibody is specific to LRRK2.
