LGALS13 Polyclonal antibody

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  WB analysis using 17823-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17823-1-AP (LGALS13 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

LGALS13 Polyclonal Antibody for WB, ELISA

Cat No. 17823-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Galectin-13, Galectin 13, Galactoside-binding soluble lectin 13, Gal-13, GAL13

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Tested Applications

• Positive WB detected in: human placenta tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

17823-1-AP targets LGALS13 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: LGALS13 fusion protein Ag12192
• Full Name: lectin, galactoside-binding, soluble, 13
• Calculated Molecular Weight: 139 aa, 16 kDa
• Observed Molecular Weight: 16 kDa
• GenBank Accession Number: BC066304
• Gene Symbol: LGALS13
• Gene ID (NCBI): 29124
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UHV8
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals.  Three of the five human cluster galectins are solely expressed in the placenta, where they may confer additional immunoregulatory functions to enable deep placentation (PMID: 25191322). One of these is galactoside-binding soluble lectin 13 (LGALS13, also known as Galectin-13 and PP13), which has a high affinity for the sugar residues of glycoproteins. PP13 is implicated in placentation and is involved in inflammation and immune defense required for trophoblast invasion during uterine artery remodeling in early pregnancy (PMID: 19497882; 10527825; 21596368; 26018511).