LARP7 Recombinant antibody

• 

  WB analysis using 84950-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84950-4-RR (LARP7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

LARP7 {ptg:Brand} Recombinant Antibody for WB, ELISA

Cat No. 84950-4-RR

Clone No.242561C10

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

PIP7S, La-related protein 7, La related protein 7, hLARP7, HDCMA18P

---

Tested Applications

• Positive WB detected in: LNCaP cells, HEK-293 cells, HeLa cells, Jurkat cells, K-562 cells, NIH/3T3 cells, HSC-T6 cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84950-4-RR targets LARP7 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: LARP7 fusion protein Ag10850
• Full Name: La ribonucleoprotein domain family, member 7
• Calculated Molecular Weight: 582 aa, 67 kDa
• Observed Molecular Weight: 67 kDa
• GenBank Accession Number: BC006981
• Gene Symbol: LARP7
• Gene ID (NCBI): 51574
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q4G0J3
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.[PMID:19416841].