Validation Data Gallery
|Sample-dependent, check data in validation data gallery|
10397-1-AP targets LAMP2 in IHC, IF, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||LAMP2 fusion protein Ag0595|
|Full Name||lysosomal-associated membrane protein 2|
|Calculated molecular weight||45 kDa|
|GenBank accession number||BC002965|
|Gene ID (NCBI)||3920|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.
Oxid Med Cell Longev
The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.
Cell Death Dis
Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.
Acta Neuropathol Commun
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.
IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.
Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.