Product Information
24871-1-PBS targets LALBA in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | LALBA fusion protein Ag21630 Predict reactive species |
Full Name | lactalbumin, alpha- |
Calculated Molecular Weight | 142 aa, 16 kDa |
Observed Molecular Weight | 13-16 kDa |
GenBank Accession Number | BC112316 |
Gene Symbol | LALBA |
Gene ID (NCBI) | 3906 |
RRID | AB_2879768 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P00709 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
LALBA encodes alpha-lactalbumin which is secreted calcium metalloprotein, a principal protein of milk. As a monomer, LALBA strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. LALBA also could form a complex with the the beta 1,4-galactosyltransferase to produce the enzyme lactose synthase, participating in the biosynthesis of lactose. Moreover, these proteins enable lactose synthase to produce lactose by transfering galactose moieties to glucose. Studies have demonstrated that LALBA-null transgenic mice showed lacking lactose in the milk and inadequate for feeding the pups (PMID:26304038; PMID:12216958).