LAG-3/CD223 Recombinant antibody, PBS Only

LAG-3/CD223 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 80867-1-PBS
Clone No.1F14

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

LAG-3, CD223, 1F14, LAG3, LAG 3

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

80867-1-PBS targets LAG-3/CD223 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen fusion protein Predict reactive species
Full Name lymphocyte-activation gene 3
Calculated Molecular Weight57 kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberNM_002286
Gene Symbol LAG-3
Gene ID (NCBI) 3902
RRIDAB_2918917
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP18627
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

LAG-3, also known as CD223, is an immune checkpoint molecule that regulates both T-cell activation and homeostasis. LAG-3 is expressed on activated T cells, NK cells, regulatory T cells, and plasmacytoid dendritic cells. It is a CD4-related molecule that binds MHC class II. LAG-3 plays an important role in modulating T cell expansion and function, and blockade of LAG-3 with monoclonal antibodies can augment T cell function. (PMID: 15634887; 21086108; 28783703)

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