KLRG1 Recombinant antibody, PBS Only

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  IF Staining of Jurkat using 84785-5-RR (same clone as 84785-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using KLRG1 antibody (84785-5-RR, Clone: 242327A4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84785-5-PBS in a different storage buffer formulation.

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  IF Staining of NK-92 using 84785-5-RR (same clone as 84785-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed NK-92 cells using KLRG1 antibody (84785-5-RR, Clone: 242327A4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84785-5-PBS in a different storage buffer formulation.

KLRG1 Uni-rAb^TM Recombinant Antibody for IF/ICC, Indirect ELISA

Cat No. 84785-5-PBS

Clone No.242327A4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Synonyms

MAFA, Killer cell lectin-like receptor subfamily G member 1, ITIM-containing receptor MAFA-L, C-type lectin domain family 15 member A, CLEC15A

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Product Information

84785-5-PBS targets KLRG1 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: killer cell lectin-like receptor subfamily G, member 1
• Calculated Molecular Weight: 22 kDa
• GenBank Accession Number: NM_005810.4
• Gene Symbol: KLRG1
• Gene ID (NCBI): 10219
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q96E93-1
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).