KIR2DL2 Polyclonal antibody

• 

  WB analysis using 31930-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31930-1-AP (KIR2DL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

KIR2DL2 Polyclonal Antibody for WB, ELISA

Cat No. 31930-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

NKAT-6, NKAT6, Natural killer-associated transcript 6, Killer cell immunoglobulin-like receptor 2DL2, CD158b1

---

Tested Applications

• Positive WB detected in: HuT 78 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31930-1-AP targets KIR2DL2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: KIR2DL2 fusion protein Ag35284
• Full Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
• Calculated Molecular Weight: 38 kDa
• Observed Molecular Weight: 60,30 kDa
• GenBank Accession Number: NM_014219
• Gene Symbol: KIR2DL2
• Gene ID (NCBI): 3803
• RRID: AB_3670150
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: P43627
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

KIR2DL2 is one of killer cell immunoglobulin-like receptors, which are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.