KIFAP3 Monoclonal antibody, PBS Only

KIFAP3 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

7C9F2

Cat no : 60266-1-PBS

Synonyms

KAP 3, KAP3, KIF3AP, KIFAP3, kinesin associated protein 3, SMAP, Smg GDS, Smg GDS associated protein

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Validation Data Gallery

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  WB analysis of human testis using 60266-1-Ig (same clone as 60266-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 60266-1-Ig (KIFAP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60266-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 60266-1-Ig (same clone as 60266-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 60266-1-Ig (KIFAP3 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 60266-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 60266-1-Ig (same clone as 60266-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 60266-1-Ig (KIFAP3 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 60266-1-PBS in a different storage buffer formulation.

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Product Information

60266-1-PBS targets KIFAP3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: KIFAP3 fusion protein Ag20809
• Full Name: kinesin-associated protein 3
• Calculated Molecular Weight: 792 aa, 91 kDa
• Observed Molecular Weight: 91-100 kDa
• GenBank Accession Number: BC028679
• Gene Symbol: KIFAP3
• Gene ID (NCBI): 22920
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

KIFAP3, also known as KIF3AP or KAP3, is a novel KIF3A/3B-associated protein. It binds to the tail domain of KIF3A/3B and may play a role in regulating the binding of KIF3A/3B to cargoes. Recently it has been reported that mutation within the KIFAP3 gene is associated with decreased KIFAP3 expression and increased survival in sporadic ALS, which makes it a potential target for ALS therapy. KIFAP3 has also been identified as the target of mir-130a.