KHSRP Polyclonal antibody, PBS Only

• 

  WB analysis using 55409-1-AP (same clone as 55409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55409-1-AP (KHSRP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55409-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 55409-1-AP (same clone as 55409-1-PBS)

  WB result of KHSRP antibody (55409-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-KHSRP transfected HeLa cells. This data was developed using the same antibody clone with 55409-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 55409-1-AP (same clone as 55409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55409-1-AP (KHSRP antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55409-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

KHSRP Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55409-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

55409-1-PBS targets KHSRP in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: KH-type splicing regulatory protein
• Calculated Molecular Weight: 73 kDa
• Observed Molecular Weight: 75 kDa
• GenBank Accession Number: NM_003685
• Gene Symbol: KHSRP
• Gene ID (NCBI): 8570
• RRID: AB_11182170
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q92945
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.