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KCNN4 Monoclonal antibody, PBS Only

KCNN4 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A6G5

Cat no : 60276-1-PBS

Synonyms

hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4

Validation Data Gallery

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  • Western Blot (WB) analysis of human blood using KCNN4 Monoclonal antibody (60276-1-Ig)

    WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 60276-1-Ig (KCNN4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60276-1-PBS in a different storage buffer formulation.

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

60276-1-PBS targets KCNN4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen KCNN4 fusion protein Ag19774
Full Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Calculated Molecular Weight 427 aa, 48 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC015337
Gene Symbol KCNN4
Gene ID (NCBI) 3783
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).