Jagged1 Recombinant antibody, PBS Only

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  WB analysis of HepG2 using 84694-1-RR (same clone as 84694-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 84694-1-RR (Jagged1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84694-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84694-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84694-1-RR against Human Jagged1 were performed. The affinity constant is 0.688 nM.

Jagged1 {ptg:Brand} Recombinant Antibody for WB, Indirect ELISA

Cat No. 84694-1-PBS

Clone No.241412F1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

JAG1, Protein jagged-1, HJ1, CD339, 241412F1

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Product Information

84694-1-PBS targets Jagged1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: jagged 1 (Alagille syndrome)
• Calculated Molecular Weight: 1218 aa, 134 kDa
• Observed Molecular Weight: 150 kDa
• GenBank Accession Number: BC098393
• Gene Symbol: Jagged1
• Gene ID (NCBI): 182
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P78504
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).