Product Information
25979-1-PBS targets JPH1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | JPH1 fusion protein Ag23270 Predict reactive species |
Full Name | junctophilin 1 |
Calculated Molecular Weight | 72 kDa |
Observed Molecular Weight | 72 kDa |
GenBank Accession Number | BC140875 |
Gene Symbol | JPH1 |
Gene ID (NCBI) | 56704 |
RRID | AB_2880317 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9HDC5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Junctophilin-1 is a protein that in humans is encoded by the JPH1 gene. This gene is a member of the junctophilin gene family. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.