JAM-A/Junctional Adhesion Molecule A Recombinant antibody

JAM-A/Junctional Adhesion Molecule A Uni-rAb^TM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

242290C2

Cat no : 84720-2-RR

Synonyms

F11R, JAM 1, JAM, F11 receptor, CD321

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Validation Data Gallery

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  WB analysis of HUVEC using 84720-2-RR

  HUVEC cells were subjected to SDS PAGE followed by western blot with 84720-2-RR (JAM-A/Junctional Adhesion Molecule A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human peripheral blood platelets using 84720-2-RR

  human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 84720-2-RR (JAM-A/Junctional Adhesion Molecule A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HUVEC cells, human peripheral blood platelets

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84720-2-RR targets JAM-A/Junctional Adhesion Molecule A in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: F11 receptor
• Calculated Molecular Weight: 33kDa
• Observed Molecular Weight: 38 kDa
• GenBank Accession Number: NM_016946.6
• Gene Symbol: F11R
• Gene ID (NCBI): 50848
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The F11 receptor (F11R) was first identified in human platelets as a 32/35 kDa protein duplex that serves as the receptor for a functional antibody that activates platelets. It seems to play a role in epithelial tight junction formation. It was also reported to function as a receptor for reovirus and a ligand for the integrin LFA1.