ISLR Polyclonal antibody

ISLR Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 24306-1-AP

Synonyms

UNQ189/PRO215, Immunoglobulin superfamily containing leucine-rich repeat protein, HsT17563

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Validation Data Gallery

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  WB analysis using 24306-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 24306-1-AP (ISLR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 24306-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 24306-1-AP (ISLR antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: NIH/3T3 cells, rat thyroid gland tissue, mouse retina tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

24306-1-AP targets ISLR in WB, ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ISLR fusion protein Ag19446
• Full Name: immunoglobulin superfamily containing leucine-rich repeat
• Calculated Molecular Weight: 428 aa, 46 kDa
• Observed Molecular Weight: 44-46 kDa
• GenBank Accession Number: BC022478
• Gene Symbol: ISLR
• Gene ID (NCBI): 3671
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The Immunoglobulin superfamily containing leucine-rich repeat protein(ISLR), is involved in various biological events, such as embryonic development, Gaucher's disease, and replicative senescence of fibroblasts in some organs, including the heart, pancreas, and bone marrow. ISLR, also known as meflin, is a newly discovered marker of mesenchymal stem cells, which is involved in pathological fibrosis and the cancer microenvironment. (PMID: 34713300)