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IL-4RA Monoclonal antibody, PBS Only

IL-4RA Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1E4C11

Cat no : 67051-1-PBS

Synonyms

IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using IL-4RA Monoclonal antibody (67051-1-Ig)

    WB analysis using 67051-1-Ig (same clone as 67051-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67051-1-Ig (IL-4R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67051-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of MG-63 cells using IL-4RA Monoclonal antibody (67051-1-Ig)

    WB analysis of MG-63 using 67051-1-Ig (same clone as 67051-1-PBS)

    MG-63 cells were subjected to SDS PAGE followed by western blot with 67051-1-Ig (IL-4R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67051-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using IL-4RA Monoclonal antibody (67051-1-Ig)

    WB analysis using 67051-1-Ig (same clone as 67051-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67051-1-Ig (IL4R antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67051-1-PBS in a different storage buffer formulation.

Product Information

67051-1-PBS targets IL-4RA in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen IL-4RA fusion protein Ag28411
Full Name interleukin 4 receptor
Calculated Molecular Weight 90 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberNM_000418
Gene Symbol IL-4R
Gene ID (NCBI) 3566
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.