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IL-2RG Polyclonal antibody, PBS Only

IL-2RG Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11409-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using IL-2RG Polyclonal antibody (11409-1-AP)

    WB analysis using 11409-1-AP (same clone as 11409-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11409-1-AP (IL2RG antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11409-1-PBS in a different storage buffer formulation.

Product Information

11409-1-PBS targets IL-2RG in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IL-2RG fusion protein Ag1911
Full Name interleukin 2 receptor, gamma (severe combined immunodeficiency)
Calculated Molecular Weight 369 aa, 42 kDa
Observed Molecular Weight 64-70 kDa
GenBank Accession NumberBC014972
Gene Symbol IL2RG
Gene ID (NCBI) 3561
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL-2RA), beta (IL-2RB), and gamma (IL-2RG). IL-2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL-2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.