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IL-29 Monoclonal antibody, PBS Only (Capture)

IL-29 Monoclonal Antibody for WB, Sandwich ELISA, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Sandwich ELISA, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H3A3

Cat no : 66163-1-PBS

Synonyms

Cytokine Zcyto21, IFN lambda 1, IFNL1, IL 29, IL29, IL-29, Interferon lambda 1, Interleukin 29, ZCYTO21

Validation Data Gallery

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  • Western Blot (WB) analysis of Recombinant protein using IL-29 Monoclonal antibody (66163-1-Ig)

    WB analysis of Recombinant protein using 66163-1-Ig (same clone as 66163-1-PBS)

    GST tagged recombinant IL29 protein were subjected to SDS PAGE followed by western blot with 66163-1-Ig (IL-29 antibody at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66163-1-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP50009-1

    Sandwich ELISA standard curve of MP50009-1

    Sandwich ELISA standard curve ofMP50009-1, IL-29 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66163-1-PBS. Detection antibody: 68671-1-PBS. Standard: HZ-1156. Range: 62.5-4000 pg/mL.

Product Information

66163-1-PBS targets IL-29 as part of a matched antibody pair:

MP50009-1: 66163-1-PBS capture and 68671-1-PBS detection (validated in Sandwich ELISA)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen IL-29 fusion protein Ag12444
Full Name interleukin 29 (interferon, lambda 1)
Calculated Molecular Weight 200 aa, 22 kDa
Observed Molecular Weight 22 kDa
GenBank Accession NumberBC074985
Gene Symbol IL-29
Gene ID (NCBI) 282618
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer 100% PBS pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family, which has another two subfamilies IL-28A and IL-28B. They are also known as IFN-λ1, IFN-λ2 and IFN-λ3, respectively. IL-29 is produced predominantly by maturing dendritic cells and macrophages. IL-29 plays an important role in the immune response against pathogenes and especially against viruses by mechanisms similar to type I interferons. IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production of antiviral proteins.