Product Information
22646-1-PBS targets IL-28A in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | IL-28A fusion protein Ag18525 Predict reactive species |
Full Name | interleukin 28A (interferon, lambda 2) |
Calculated Molecular Weight | 200 aa, 22 kDa |
GenBank Accession Number | BC113583 |
Gene Symbol | IL-28A |
Gene ID (NCBI) | 282616 |
RRID | AB_2879141 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8IZJ0 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
IL28A, also named as IFNL2 and ZCYT020, is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. IL28A is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. It plays a significant role in the antiviral immune defense in the intestinal epithelium.