IL-23R Polyclonal antibody, PBS Only

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  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

IL-23R Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 27163-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

IL23R, Interleukin-23 receptor, interleukin 23 receptor, IL-23 receptor, IL 23R

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Product Information

27163-1-PBS targets IL-23R in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IL-23R fusion protein Ag25939
• Full Name: interleukin 23 receptor
• Calculated Molecular Weight: 72 kDa
• Observed Molecular Weight: 65-75 kDa
• GenBank Accession Number: NM_144701
• Gene Symbol: IL-23R
• Gene ID (NCBI): 149233
• RRID: AB_2880783
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939).