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IL-20 Polyclonal antibody, PBS Only

IL-20 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18104-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using IL-20 Polyclonal antibody (18104-1-AP)

    WB analysis of HEK-293 using 18104-1-AP (same clone as 18104-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 18104-1-AP (IL20 Antibody) at dilution of 1:700 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using IL-20 Polyclonal antibody (18104-1-AP)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using IL-20 Polyclonal antibody (18104-1-AP)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

Product Information

18104-1-PBS targets IL-20 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IL-20 fusion protein Ag12447
Full Name interleukin 20
Calculated Molecular Weight 406 aa, 44 kDa
GenBank Accession NumberBC074949
Gene Symbol IL-20
Gene ID (NCBI) 50604
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 receptor (IL-20R) and IL-20 are expressed in several normal tissue types, including the lung, skin, and kidney. IL-20 is a cytokine structurally related to interleukin 10. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 can stimulate STAT3 activation in keratinocytes. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. IL-20 is highly associated with potent inflammatory diseases such as psoriasis, contact hypersensitivity, rheumatoid arthritis, and atherosclerosis.