Product Information
66143-1-PBS targets IL-17D in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | IL-17D fusion protein Ag6762 Predict reactive species |
Full Name | interleukin 17D |
Calculated Molecular Weight | 22 kDa |
Observed Molecular Weight | 28 kDa |
GenBank Accession Number | BC036243 |
Gene Symbol | IL-17D |
Gene ID (NCBI) | 53342 |
RRID | AB_2881540 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q8TAD2 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IL17D is a secreted cytokine with homology to the IL-17 family of proteins. IL17D is preferentially expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. The treatment of endothelial cells with IL17D has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by IL17D was found to be NF-kappa B-dependent.