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IL-16 Monoclonal antibody, PBS Only

IL-16 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C4C7

Cat no : 66145-1-PBS

Synonyms

HsT19289, IL 16, IL16, IL-16, LCF, prIL 16, Pro interleukin 16

Validation Data Gallery

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  • Western Blot (WB) analysis of Recombinant protein using IL-16 Monoclonal antibody (66145-1-Ig)

    WB analysis of Recombinant protein using 66145-1-Ig (same clone as 66145-1-PBS)

    Recombinant protein were subjected to SDS PAGE followed by western blot with 66145-1-Ig (IL-16 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66145-1-PBS in a different storage buffer formulation.

Product Information

66145-1-PBS targets IL-16 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen IL-16 fusion protein Ag16466
Full Name interleukin 16 (lymphocyte chemoattractant factor)
Calculated Molecular Weight 130 aa, 15 kDa
Observed Molecular Weight 37 kDa
GenBank Accession NumberBC040272
Gene Symbol IL-16
Gene ID (NCBI) 3603
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.