IHCeasy Nectin-2/PVRL2 Ready-To-Use IHC Kit
Nectin-2/PVRL2 Ready-to-use reagent kit for IHC.
Cat no : KHC0114
CD112, Herpes virus entry mediator B, Herpesvirus entry mediator B, HVEB, Nectin-2, PRR2, PVRL2, PVRR2
KHC0114 is a ready-to-use IHC kit for staining of Nectin-2 (also named PVRL2). The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy Nectin-2/PVRL2 Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
Nectin 2, also named as PVRL2, CD112, HVEB, PRR2 and PVRR2, is an adhesion molecule widely expressed in cell lines of different lineages, including hematopoietic, neuronal, endothelial and epithelial cells. CD112 belongs to a new family of immunoglobulin-like molecules that includes four members (CD111, CD112, PRR3 and CD155) sharing an ectodomain made of three Ig domains, of V, C, C types. CD112 is expressed in the myelo-monocytic and megakaryocytic hematopoietic lineages and the function in hematopoiesis is currently unknown. CD112 is an intercellular homophilic adhesion. CD112 localizes specifically at adherents junctions via its cytoplasmic interaction with the scaffold F-actin binding protein afadin. Disruption of the murine CD112 gene leads to infertility of male mice with morphologically aberrant spermatozoa. CD112 mediates entry of some alphaherpesvirus mutants (also named HveB) via its V domain. CD112 is involved in cell to cell spreading of viruses.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|CD112, Herpes virus entry mediator B, Herpesvirus entry mediator B, HVEB, Nectin-2, PRR2, PVRL2, PVRR2