IHCeasy GSK3A Ready-To-Use IHC Kit
GSK3A Ready-to-use reagent kit for IHC.
Cat no : KHC2292
Synonyms
Serine/threonine-protein kinase GSK3A, GSK-3 alpha, GSK 3 alpha, Glycogen synthase kinase-3 alpha, EC:2.7.11.26
Validation Data Gallery
Product Information
KHC2292 is a ready-to-use IHC kit for staining of GSK3A. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
| Product name | IHCeasy GSK3A Ready-To-Use IHC Kit |
| Sample type | FFPE tissue |
| Assay type | Immunohistochemistry |
| Primary antibody type | Rabbit Polyclonal |
| Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
| Reactivity | Human, Mouse, Rat |
Kit components
| Component | Size | Concentration |
|---|---|---|
| Antigen Retrieval Buffer | 100 mL | 50× |
| Washing Buffer | 100 mL ×2 | 20× |
| Blocking Buffer | 5 mL | RTU |
| Primary Antibody | 5 mL | RTU |
| Secondary Antibody | 5 mL | RTU |
| Chromogen Component A | 0.2 mL | RTU |
| Chromogen Component B | 4 mL | RTU |
| Signal Enhancer | 5 mL | RTU |
| Counter Staining Reagent | 5 mL | RTU |
| Mounting Media | 5 mL | RTU |
| Datasheet | 1 Copy | |
| Manual | 1 Copy |
Background Information
GSK3A (glycogen synthase kinase 3 alpha), one of the two functional isoforms encoded by the GSK3 gene, is a serine/threonine protein kinase that is involved in cell-cycle progression, differentiation, and apoptosis. GSK3A acts as a tumor suppressor and has important roles in acute myeloid leukemia (AML), prostate cancer, and pancreatic cancer. GSK3A is also known to interact with beta-amyloid and tau, proteins that aggregate in areas of the neuronal system as part of the pathology of neurodegenerative diseases such as Alzheimer's disease.
Properties
| Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
| Synonyms | Serine/threonine-protein kinase GSK3A, GSK-3 alpha, GSK 3 alpha, Glycogen synthase kinase-3 alpha, EC:2.7.11.26 |