IHCeasy AXIN2 Ready-To-Use IHC Kit
AXIN2 Ready-to-use reagent kit for IHC.
Cat no : KHC0473
AXIL, axin 2, Axin like protein, AXIN2, Axis inhibition protein 2, Conductin
KHC0473 is a ready-to-use IHC kit for staining of AXIN2. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy AXIN2 Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
Axis inhibition protein2 (AXIN2), also known as Coductin or Axil, is a multidomain scaffold protein that negatively regulate Wnt signaling. AXIN2 can directly interact with beta-catenin and GSK3B. AXIN2 has a number of phosphorylation sites, and also can undergo poly(ADP-ribosy)lation by tankyrase TNKS and TNKS2. Poly(ADP-ribosy)lated AXIN2 then get unbiquitinated by RNF146 and leads to its degradation and subsequent activation of Wnt signaling. AXIN2 is localized in the cytoplasm and its mutaion is involved in colorectal cancer.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|AXIL, axin 2, Axin like protein, AXIN2, Axis inhibition protein 2, Conductin