IHCeasy ATP1A3 Ready-To-Use IHC Kit
ATP1A3 Ready-to-use reagent kit for IHC.
Human, Mouse, Rat
Cat no : KHC1274
ATP1A3, ATP1A3 (C-terminal), DYT12, RDP, Sodium pump subunit alpha 3
KHC1274 is a ready-to-use IHC kit for staining of ATP1A3. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy ATP1A3 Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Human, Mouse, Rat
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
ATP1A3 participates in the catalyticing hydrolysis of ATP and the exchanging of sodium and potassium ions across plasma membrane. The catalyticing activity mode is ATP + H2O + Na+(In) + K+(Out) = ADP + phosphate + Na+(Out) + K+(In). It has been published that the neurologic disorders rapid-onset dystonia-parkionsonism (RDP), alternating hemiplegia of childhood (ACH) and CAPOS syndrome (cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorineural hearing loss) are all related with the mutation of ATP1A3. There are other reports suggest that early life epilepsy and episodic apnea revealing are potentially associated with the mutation of ATP1A3 as a result of impairment of Na/K homeostasis. Primary antibody in this kit is generated against the C-terminal region (665-1013aa) of ATP1A3.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|ATP1A3, ATP1A3 (C-terminal), DYT12, RDP, Sodium pump subunit alpha 3