IGF2BP2 Monoclonal antibody, PBS Only

IGF2BP2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1E5H8

Cat no : 60647-1-PBS

Synonyms

insulin like growth factor 2 mRNA binding protein 2, IMP-2, IMP2, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2

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Validation Data Gallery

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  WB analysis using 60647-1-Ig (same clone as 60647-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60647-1-Ig (IGF2BP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60647-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 60647-1-Ig (same clone as 60647-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60647-1-Ig (IGF2BP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60647-1-PBS in a different storage buffer formulation.

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Product Information

60647-1-PBS targets IGF2BP2 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: IGF2BP2 fusion protein Ag33681
• Full Name: insulin-like growth factor 2 mRNA binding protein 2
• Calculated Molecular Weight: 65 kDa
• Observed Molecular Weight: 65-70 kDa
• GenBank Accession Number: BC021290
• Gene Symbol: IGF2BP2
• Gene ID (NCBI): 10644
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2), ia a member of a family of mRNA binding protein, which can bind to several mammalian cells' mRNAs. Thus it may involve in the regulation of translation of mRNA. IGF2BP2's polymorphisms is risk factor for developing type 2 diabetes. This antibody raise against part of N-terminus of human IGF2BP2. IGF2BP2 has some isoforms with the MW of 54-66 kDa. Some literature has reported that multiple bands can be detected (PMID: 22427968, 36322753, 23069990).